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In the late 16th century, the Spanish doctor Nicolas Monardes claimed that tobacco alleviated hunger, acted as a relaxant and a painkiller, and was even a cure for cancer

At any rate, it seems that a straight line can be drawn from Caldwell to writers such as Harry Crews, who also attempted to combine tragedy and comedy in their novels

Until the English began to establish their own settlements in the New World, tobacco was a rare luxury for Europeans that was only available through trade with the Spanish

It is addictive as it changes the way the brain works, causing cravings for more